The 856th MIB Seminar
(Joint Usage/Research Center for the Multi-stratified Host Defense System)
Title
Protein targeting to mitochondria – a big challenge for eukaryotic cells
Speaker
Prof. Johannes M. Herrmann
Cell Biology, University of Kaiserslautern, Germany
Date
Apr 16 (Thu), 2026
15:00-16:30
Venue
Seminar Room 105, 1F, Biomedical Research Station, Hospital Campus
No.34 on the following linked map.
Campus Map
Abstract
Most mitochondrial proteins are synthesized as cytosolic precursor proteins before they are imported into mitochondria. Recent in vivo studies showed that mitochondrial precursor proteins have a surprisingly complex biology before they reach the mitochondrial surface. We realized that mitochondrial precursor proteins explore the cytosol, get in contact with components of the proteasome and chaperone network and often end up on the surface or even the lumen of other cellular compartments. In my talk, I will give an overview about our current knowledge of these early reactions in mitochondrial protein targeting and present recent data from our team.
Contact
Division of Trans-Scale Structural Life Science, Medical Institute of Bioregulation
Kenji Inaba
TEL: 092 (642) 6968
E-mail: kenji.inaba[＠]bioreg.kyushu-u.ac.jp
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