The 850th MIB Seminar
(Joint Usage/Research Center for the Multi-stratified Host Defense System)
Title
Meninges-brain interaction modulates chronic kidney disease-induced neurovascular dysfunction and cognitive impairment
Speaker
Dr. Che-Feng Chang
Associate Professor
Graduate Institute of Physiology, National Taiwan University College of Medicine
Date
Apr. 2 (Wed), 2024
15：00〜16：00
Venue
Lecture Room 101, 1F, Biomedical Research Station, Hospital Campus
No.34 on the following linked map.
Campus Map
Abstract
Meningeal macrophages and lymphatic vessels act as CNS immune regulatory compartments and modulate brain cell responses and neuroinflammation in various disease models. We found that chronic kidney disease (CKD) mediated vascular IgG leakage, microglia activation, and cognitive impairment in animals. I will discuss about the role of meningeal immune cells in CKD-induced brain vessel pathologies and neurologic deficits.
Contact
Division of Allergy and Immunology, Medical Institute of Bioregulation
Minako Ito
TEL: 092 (642) 6965