Division of Bioinformatics

Our laboratory studies the molecular mechanisms involved in controlling gene expression and the evolutionary process for the regulation system. The sequences of gene expression switches tend to be evolutionarily conserved and can be identified by comparing genome sequences. Recently, in addition to the genome sequencing data from various animals such as human and mouse, more and more transcriptome data and epigenetic profile data by tissues are registered in the public databases. In our laboratory, we are trying to reveal the mechanism of gene expression and the underlying evolutionary process by integrating and analyzing the various dataset. Moreover, we are also trying to apply the knowledge to the elucidation of the causes of diseases that probably arise from abnormalities in gene expression control mechanisms.