Publication List
Research Assistant Professor : Au Yeung Wan Kin (Donald)
Original Research Papers
Toriyama, K., Au Yeung, W.K., Inoue, A., Kurimoto, K., Yabuta, Y., Saitou, M., Nakamura, T., Nakano, T. & Sasaki, H.
DPPA3 facilitates genome-wide DNA demethylation in mouse primordial germ cells.
BMC Genomics (in press).

Uehara, R., Au Yeung, W.K., Toriyama, K., Ohishi, H., Kubo, N., Toh, H., Suetake, I., Shirane, K. & Sasaki, H.
The DNMT3A ADD domain is required for efficient de novo DNA methylation and maternal imprinting in mouse oocytes.
PLoS Genet. 19:e1010855 (2023)
Pubmed

Unoki, M., Velasco, G., Kori, S., Arita, K., Daigaku, Y., Au Yeung, W.K., Fujimoto, A., Ohashi, H., Kubota, T., Miyake, K. & Sasaki, H.
Novel compound heterozygous mutations in UHRF1 are associated with atypical immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome with distinctive genome-wide DNA hypomethylation.
Hum. Mol. Genet. 32:1439-1456 (2023).
Pubmed

Maruyama, O., Li, Y., Toh, H., Au Yeung, W.K. & Sasaki, H
CMIC: Predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers.
BMC Bioinform. 23:371 (2022).
Pubmed

Hasuwa, H., Iwasaki, Y.W., Au Yeung, W.K., Ishino, K., Masuda, H., Sasaki, H. & Siomi, H.
Production of functional oocytes requires maternally expressed PIWI genes and piRNAs in golden hamsters.
Nat. Cell Biol. 23, 1002-1012 (2021)
PubMed

Au Yeung, W.K., Maruyama, O. & Sasaki, H.
A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns.
BMC Bioinform. 22, 341 (2021)
PubMed

Ishiuchi, T., Abe, S., Inoue, K., Au Yeung, W.K., Miki, Y., Ogura, A. & Sasaki, H.
Reprogramming of the histone H3.3 landscape in the early mouse embryo.
Nat. Struct. Mol. Biol. 28, 38-49 (2021)
PubMed

Cheung, M.Y., Au Yeung, W.K., Li, K.P. & Lam, H.M.
A rice immunophilin homolog, OsFKBP12, is a negative regulator of both biotic and abiotic stress responses.
Int J Mol Sci. 21, 8791 (2020)
PubMed

Richard Albert, J., Au Yeung, W.K., Toriyama, K., Kobayashi, H., Hirasawa, R., Brind'Amour, J., Bogutz, A., Sasaki, H. & Lorincz, M.
Maternal DNMT3A-dependent de novo methylation of the paternal genome inhibits gene expression in the early embryo.
Nat. Commun. 11, 5417 (2020)
PubMed

Ohishi, H.*, Au Yeung, W.K.*, Unoki, M., Ichiyanagi, K., Fukuda, K., Maenohara, S., Shirane, K., Chiba, H., Sado, T. & Sasaki, H. (*These authors equally contributed to the work.)
Characterization of genetic-origin-dependent monoallelic expression in mouse embryonic stem cells.
Genes Cells 25, 54-64 (2020)
PubMed

Du, Z., Zheng, H., Kawamura, Y.K., Zhang, K., Gassler, J., Powell, S., Xu, Q., Lin, Z., Xu, K., Zhou, Q., Ozonov, E.A., Veron, N., Huang, B., Li, L., Yu, G., Liu, L., Au Yeung, W.K., Wang, P., Chang, L., Wang, Q., He, A., Sun, Y., Na, J., Sun, Q., Sasaki, H., Tachibana, K., Peters, A.H.F.M. & Xie, W.
Polycomb group proteins regulate chromatin architecture in mouse oocytes and early embryos.
Mol. Cell 77, 825-839 (2020)
PubMed

Au Yeung, W.K., Brind'Amour, J., Hatano, Y., Yamagata, K., Feil, R., Lorincz, M.C., Tachibana, M., Shinkai, Y. & Sasaki, H.
Histone H3K9 methyltransferase G9a in oocytes is essential for preimplantation development but dispensable for CG methylation protection.
Cell Rep. 27, 282-293 (2019)
PubMed

Li, M.W., Au Yeung, W.K. & Lam, H.M.
The GCN2 homologue in Arabidopsis thaliana interacts with uncharged tRNA and uses Arabidopsis eIF2α molecules as direct substrates.
Plant Biol (Stuttg). 15, 13-18 (2013)
PubMed

Books
Au Yeung, W.K. & Sasaki, H.
Low-input genome-wide DNA methylation analysis with minimal library amplification.
In piRNA: Methods and Protocols (eds Parrish, N.F. & Iwasaki, Y.W.), pp. 233-250, Methods in Molecular Biology Series, Springer US (2022)

Ku, Y.S., Au Yeung, W.K., Yung, Y.L., Li, M.W., Wen, C., Liu, X. & Lam, H.M.
Drought Stress and Tolerance in Soybean.
A Comprehensive Survey of International Soybean Research - Genetics, Physiology, Agronomy and Nitrogen Relationships 129-146, InTech (2013)

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