| 研究業績 |
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| 欧文・欧文総説 |
| 2025年 |
*Miura S., *Horisawa K., Inada H., Sakaguchi Y., Yorino M., Suzuki A.
(* Co-first author) Activation of canonical Wnt sgnaling is required for efficient direct reprogramming into human hepatic progenitor cells. Stem Cell Reports 20, 102688, 2025. 【PubMed】
Murayama R., Horisawa K., Miura S., Taniguchi S., Shu J., Takahashi M.,
Izumi Y., Bamba T., Ishigami K., Suzuki A. Differential effects of liver
regeneration on
aging-related changes in gene expression and metabolic function.
Aging Cell, e70197. 【PubMed】
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| 2024年 |
Miura S., Horisawa K., Iwamori T., Tsujino S., Inoue K., Karasawa S., Yamamoto J.,
Ohkawa Y., Sekiya S., Suzuki A.
Hepatocytes differentiate into intestinal epithelial cells through a hybrid
epithelial/mesenchymal
cell state in culture.
Nat Commun, 15,3940. 【PubMed】
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| 2023年 |
Horisawa K., Miura S., Araki H., Miura F., Ito T., Suzuki A.
Transcription factor-mediated direct cellular reprogramming yields cell-type specific
DNA methylation signature.
Sci Rep, 13, 22317. 【PubMed】
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| 2020年 |
Miura S. and Suzuki A.
Direct lineage reprogramming of mouse fibroblasts to acquire the identity
of fetal
intestine-derived progenitor cells.
Methods Mol Biol, 2171, Humana Press Inc., p.231-236.
Miura S., and Suzuki A.
Induction of Steatohepatitis and Liver Tumorigenesis by
Enforced Snail Expression in Hepatocytes.
The American Journal of Pathology190, 1271-1283.
【PubMed】
|
| 2018年 |
Yamamoto J., Udono M., Miura S., Sekiya S., Suzuki A.
Cell aggregation culture induces functional differentiation of
induced hepatocyte-like cells through activation of
Hippo signaling.
Cell Rep 25, 183-198. 【PubMed】
Miura S,. and Suzuki A.
Brief summary of the current protocols forgenerating
intestinal organoids.
Develop Growth Differ 60, 387-392.
【PubMed】
|
| 2017年 |
Miura S,. and Suzuki A.
Generation of mouse and humanorganoid-formingintestinal
progenitor cells by direct lineagereprogramming.
Cell Stem Cell 21, 456-471. 【PubMed】
|
| 2016年 |
*Sekiya S., *Miura S., *Matsuda-Ito K., Suzuki A.
Myofibroblasts derived from hepatic progenitor cells create the
tumor microenvironment.
Stem Cell Reports 7, 1130-1139. (* Co-first author) 【PubMed】
Terada M., Horisawa K., Miura S., Takashima Y., Ohkawa Y.,
Sekiya S.,Matsuda-Ito K., Suzuki A.
Kupffer cells induce Notch-mediated hepatocyte conversion in a
common mouse model of intrahepatic cholangiocarcinoma.
Sci Rep 6, 34691. 【PubMed】
Takashima Y., Terada M., Udono M., Miura S., Yamamoto J.,
Suzuki A.
Suppression of lethal-7b and miR-125a/b maturation by Lin28b
enables maintenance of stem cell properties in hepatoblasts.
Hepatology 64, 245-260. 【PubMed】
|
| 2014年 |
Miura S., and Suzuki A.
Rapid cell-fate conversion of mouse fibroblastsinto
hepatocyte-like cells.
Inflamm Renen 34, 211-216. 【PubMed】
Miura S., and Suzuki A.
Acquisition of lipid metabolic capability in hepatocyte-like cells
directly induced from mouse fibroblasts.
Front Cell Dev Biol 2, 1-6. 【PubMed】
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邦文総説
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| 2017年 |
三浦静、鈴木淳史
「ダイレクトリプログラミング法によるオルガノイド形成能をもつ
マウスおよびヒトの腸前駆細胞の作製」
ライフサイエンス新着論文レビュー
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