嬨廈戝妛惗懱杊屼堛妛尋媶強

嵶朎婡擻惂屼妛晹栧


Division of Organogenesis and Regeneration
Medical Institute of Bioregulation, Kyushu University
Top Research Publication Members Event Links Access
尋媶嬈愌
墷暥墷暥憤愢
2023擭



Kawamata M, Suzuki H, Kimura R,Suzuki A
Optimization of Cas9 activity through the addition of cytosine extensions to single-guide RNAs.
Nat Biomed Eng,in press,37037965. 丂亂PubMed


2020擭

Katsuda T., Kawamata M., Inoue A., Yamaguchi T., Abe M., Ochiya T.
Long-term maintenance of functional primary human hepatocytes
using small molecules.
FEBS Lett., 594(1):114-125. 亂PubMed


2019擭

Terada M., Kawamata M., Kimura R., Sekiya S., Nagamatsu G.,
Hayashi K., Horisawa K., Suzuki A.
Generation of Nanog reporter micethat distinguish pluripotent stem cells
from unipotent primordial germ cells.
Genesis57(11-12):e23334. 
PubMed


2018擭

Yoshimura A., Adachi N., Matsuno H., Kawamata M., Yoshioka Y.,
Kikuchi H., Odaka H., Numakawa T., Kunugi H., Ochiya T., Tamai Y.
The Sox2 promoter-driven CD63-GFP transgenic rat model allows
tracking of neural stem cell-derived extracellular vesicles.
Dis Model Mech. 30;11(1). pii: dmm028779.亂PubMed



2017擭

Kawamata M., Katsuda T., Yamada Y., Ochiya T.
In vitro reconstitution of breast cancer heterogeneity with multipotent
cancer stem cells using small molecules.
Biochem Biophys Res Commun
. 2017, 482(4):750-75

PubMed


Kawamata M., Suzuki A.
Cell fate modification toward the hepatic lineageby extrinsic factors.
J Biochem
. 162(1):11-16. 亂PubMed


Katsuda T., Kawamata M., Hagiwara K., Takahashi RU., Yamamoto Y.,
Camargo FD, Ochiya T.
Conversion of terminally committed hepatocytes to culturable bipotent
progenitor cells with regenerative capacity.
Cell Stem Cell, 2017, 20(1):41-55.  亂PubMed



2016擭 Yoshimura A., Kawamata M., Yoshioka Y., Katsuda T., Kikuchi H., Nagai Y.,
Adachi N., Numakawa T., Kunugi H., Ochiya T., Tamai Y.
Generation of a novel transgenic rat model for tracing extracellular vesicles
in body fluids.
Sci Rep, 2016, 6: 31172
PubMed


2015擭 Kawaharada K., Kawamata M., Ochiya T.丂
Rat embryonic stem cells create new era in development of genetically
manipulated rat models.
World J Stem Cells. 26;7(7):1054-63
PubMed


2014擭 Katsuda T., Ikeda S., Yoshioka Y., Kosaka N., Kawamata M., Ochiya T.
Physiological and pathological relevance of secretory microRNAs and
perspective on their clinical application.
Biol Chem,
395(4):365-73 PubMed



2013擭

Hong J, He H, Bui P, Ryba-White B, Rumi MA, Soares MJ, Dutta D,
Paul S, Kawamata M., Ochiya T.,Ying QL, Rajanahalli P, Weiss ML.
A Focused Microarray for Screening Rat Embryonic Stem Cell Lines.
Stem Cells Dev,
22(3):431-43
PubMed


2012擭 Kawamata M., Ochiya T.
Two distinct knockout approaches highlight a critical role for p53
in rat development.
Sci Rep
, 2: 945
PubMed


2011擭 Kawamata M., Ochiya T.
Gene-manipulated embryonic stem cells forrat transgenesis.
Cell Mol Life Sci. 68(11):1911-5
PubMed


Kawamata M., Ochiya T.
Establishment of embryonic stem cells and generation of
genetically modified rats.
InTech
,p383-96
PubMed


2010擭 Kawamata M., Ochiya T.
Generation of genetically modified rats from embryonic stem cells.
Proc Natl Acad Sci USA
.10;107(32):14223-8

PubMed


Takeshita F., Patrawala L, Osaki M., Takahashi RU, Yamamoto Y,
Kosaka N., Kawamata M., Kelnar K, Bader AG, Brown D, Ochiya T.
Systemic delivery of synthetic microRNA-16 inhibits the growth of
metastatic prostate tumors via downregulation of multiple cell-cycle genes.
Mol Ther,
18(1):181-7.
PubMed


Kawamata M., Ochiya T.
Establishment of embryonic stem cellsfrom rat blastocysts.
Methods Mol Biol
. 597:169-77
PubMed


2008擭 Kawamata M., Yoshida M., Sugimoto Y., Kimura T., Tonomura Y.,
Takayanagi Y., Yanagisawa T., Nishimori K.
Infusion of oxytocininduces successful delivery in prostanoid
FP-receptor-deficient mice.
Mol Cell Endocrinol. 283(1-2):32-7
PubMed


Banas A, Teratani T., Yamamoto Y., Tokuhara M., Takeshita F.,
Kawamata M., Kato T., Okochi H., Ochiya T.
In vivo therapeutic potential of human Adipose Tissue Mesenchymal
Stem Cells(AT-MSCs) after transplantation into mice with liver injury.
Stem Cells,
26(10):2705-12
PubMed


Ueda S., Kawamata M., Teratani T., Shimizu T., Tamai Y., Ogawa H.,
Hayashi K., Tsuda H., Ochiya T.
Establishment of rat embryonic stem cells and making of chimera rats.
PLoS One
, 3(7):e2800
PubMed


Nishimori K., Takayanagi Y., Yoshida M., Kasahara Y., Young LJ,
Kawamata M.
New aspects of oxytocin receptor function revealed by knockout mice:
sociosexual behaviour and control of energy balance.
Prog Brain Res.
170:79-90
PubMed


2007擭 Kawamata M., Inoue H., Nishimori K.
Male-specific function of Dmrt7 by sexually dimorphic translation
in mouse testis.
Sex Dev.2007;1(5):297-304
PubMed


Kawamata M., Tonomura Y., Kimura T., Sugimoto Y., Yanagisawa T.,
Nishimori K.
Oxytocin-induced phasic and tonic contractions are modulated
by the contractilemachinery rather than the quantity of oxytocin receptor.
Am J Physiol Endocrinol Metab
. 292(4):E992-9

PubMed



2006擭 Kawamata M., Nishimori K.
Mice deficient in Dmrt7 show infertility with spermatogenic arrest at
pachytene stage.
FEBS Lett. 580(27):6442-6 PubMed



2005擭 Takayanagi Y., Yoshida M., Bielsky IF, Ross HE, Kawamata M., Onaka T.,
Yanagisawa T., Kimura T., Matzuk MM, Young LJ, Nishimori K.
Pervasive social deficits, but normal parturition, in oxytocin
receptor-deficient mice.
Proc Natl Acad Sci USA.
102(44):16096-101PubMed



2004擭 Kawamata M., Tonomura Y., Kimura T., Yanagisawa T., Nishimori K.
The differential coupling of oxytocin receptors to uterine contractions
in murine estrous cycle.
Biochem Biophys Res Commun
. 321(3):695-9PubMed



2003擭 Kawamata M., Mitsui-Saito M., Kimura T., Takayanagi Y., Yanagisawa T.,
Nishimori K.
Vasopressin-induced contraction of uterus is mediated solely by
the oxytocin receptor in mice, but not in humans.
Eur J Pharmacol 472(3): 229-34PubMed