Medical Institute of Bioregulation, Kyushu University

Publications List　(Significant Paper)

FY 2023

• H3K4me1 facilitates promoter-enhancer interactions and gene activation during embryonic stem cell differentiation. Molecular Cell (IF=16.0) 【Sasaki Laboratory (Epigenomics and Development)】(2024.03.21)
• Structure of full-length ERGIC-53 in complex with MCFD2 for cargo transport. Nature Commun. (IF=16.6) 【Division of Trans-Scale Structural Life Science】(2024.03.16)
• The complex etiology of autism spectrum disorder due to missense mutations of CHD8. Mol. Psychiatry (IF=11.0) 【Division of Cell Biology】(2024.03.05)
• STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells. J. Exp. Med. (IF=15.3) 【Division of Immunology and Genome Biology】(2023.10.30)
• Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn²⁺ uptake into the Golgi apparatus. Nature Commun. (IF=16.6) 【Division of Trans-Scale Structural Life Science】(2023.08.08)
• Molecular evolution of Keap1 was essential for adaptation of vertebrates to terrestrial life. Science Advances (IF=14.980) 【Division of Cell Biology】(2023.05.19) RESEARCH RESULTS
• Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface. Nature Commun. (IF=17.694) 【Division of Trans-Scale Structural Life Science】(2023.05.09) RESEARCH RESULTS
• The ASC-1 complex promotes translation initiation by scanning ribosomes. EMBO J. (IF=13.783) 【Division of Cell Biology】(2023.04.24)
• RPL3L-containing ribosomes determine translation elongation dynamics required for cardiac function. Nature Commun. (IF=17.694) 【Division of Cell Biology】(2023.04.20)
• Optimization of Cas9 activity through the addition of cytosine extensions to single-guide RNAs. Nat Biomed Eng. (IF=29.234) 【Division of Organogenesis and Regeneration】(2023.04.11)

FY 2022

• Ablation of p57+ quiescent cancer stem cells suppresses recurrence after chemotherapy of intestinal tumors. Cancer Res. (IF=13.312) 【Division of Cell Biology】(2023.03.08)
• DOCK2 regulates MRGPRX2/B2-mediated mast cell degranulation and drug-induced anaphylaxis. J. Allergy Clin. Immunol.（IF=14.290）【Division of Immunogenetics】(2023.02.16)
• Histone H3K36me2 and H3K36me3 form a chromatin platform essential for DNMT3A-dependent DNA methylation in mouse oocytes. Nature Commun. (IF=17.694) 【Division of Epigenomics and Development】(2022.08.03)
• Identification of a functional DOCK8 gene polymorphism associated with atopic dermatitis. Allergy (IF=14.710) 【Division of Immunogenetics】(2022.07.16)

FY 2021

• Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium. Nature Commun. (IF=14.919) 【Division of Cell Biology】(2022.03.21)
• Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis. Nature Commun. (IF=14.919) 【Division of Cell Biology】【Division of Metabolomics】【Division of Bioinformatics】(2022.02.28)
• Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant. Nucleic Acids Res. (IF=16.971) 【Division of Transcriptomics】(2021.12.21)
• Modeling population size independent tissue epigenomes by ChIL-seq with single thin sections. Mol Syst Biol. (IF=11.429) 【Division of Transcriptomics】(2021.11.04)
• High-depth spatial transcriptome analysis by photo-isolation chemistry. Nature Commun. (IF=14.919) 【Division of Transcriptomics】(2021.07.20)
• Combinatorial analysis of translation dynamics reveals eIF2 dependence of translation initiation at near-cognate codons. Nucleic Acids Res. (IF=16.971) 【Division of Cell Biology】(2021.07.06)
• Targeted inhibition of EPAS1–driven IL-31 production by a small-molecule compound. J. Allergy Clin. Immunol. (IF=10.228) 【Division of Immunogenetics】【Division of Transcriptomics】(2021.04.02)

FY 2020

• POINT technology illuminates the processing of polymerase-associated intact nascent transcripts. Molecular Cell (IF=15.584) 【Division of Cancer Genome Regulation】(2021.03.17)
• Reprogramming of the histone H3.3 landscape in the early mouse embryo. Nat. Struct. Mol. Biol. (IF=11.980) 【Division of Epigenomics and Development】(2020.11.10)
• Direct reprogramming of human umbilical vein- and peripheral blood-derived endothelial cells into hepatic progenitor cells. Nature Commun. (IF=12.121) 【Division of Organogenesis and Regeneration】【Division of Transcriptomics】【Division of Bioinformatics】(2020.10.21) RESEARCH RESULTS PRESS RELEASE
• Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation. Nature Commun. (IF=12.121) 【Division of Cell Biology】(2020.09.11)
• Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input. Nat Protoc. (IF=10.419) 【Division of Transcriptomics】(2020.08.17)
• The Dynamics of Transcriptional Activation by Hepatic Reprogramming Factors. Molecular Cell
  (IF=15.584) 【Division of Organogenesis and Regeneration】【Division of Transcriptomics】(2020.08.05) RESEARCH RESULTS PRESS RELEASE
• Tet2 and Tet3 in B Cells Are Required to Repress CD86 and Prevent Autoimmunity. Nat. Immunol. (IF=23.530) 【Division of Immunology and Genome Biology】 (2020.06.22)