特任教授:佐々木 裕之
原著論文 Original Research Papers / 英文 English (1990年以前25編は省略)
- Toriyama, K., Au Yeung, W.K., Inoue, A., Kurimoto, K., Yabuta, Y., Saitou, M., Nakamura, T., Nakano, T. & Sasaki, H.
- DPPA3 facilitates genome-wide DNA demethylation in mouse primordial germ cells.
- BMC Genomics (in press).
- Kubo, N., Chen, P.B., Hu, R., Ye, Z., Sasaki, H. & Ren, B.
- H3K4me1 facilitates promoter-enhancer interactions and gene activation during embryonic stem cell differentiation.
- Mol. Cell 84, 1-11 (2024).
- Toh, H. & Sasaki, H.
- Spatiotemporal DNA methylation dynamics shape megabase-scale methylome landscapes.
- Life Sci. Alliance 7, e202302403 (2024).
- Pubmed
- Uehara, R., Au Yeung, W.K., Toriyama, K., Ohishi, H., Kubo, N., Toh, H., Suetake, I., Shirane, K. & Sasaki, H.
- The DNMT3A ADD domain is required for efficient de novo DNA methylation and maternal imprinting in mouse oocytes.
- PLoS Genet. 19:e1010855 (2023)
- Pubmed
- Sakamoto, M., Abe, S., Miki, Y., Miyanari, Y., Sasaki, H. & Ishiuchi, T.
- Dynamic nucleosome remodeling mediated by YY1 underlies early mouse development.
- Genes Dev. 39: 590-604 (2023).
- Pubmed
- Uemura, S., Maenohara, S., Inoue, K., Ogonuki, N., Matoba, S., Ogura, A., Kurumizaka, M., Yamagata, K., Sharif, J., Koseki, H., Ueda, K., Unoki, M. & Sasaki, H.
- UHRF1 is essential for proper cytoplasm architecture and function of mouse oocyte and derived embryo.
- Life Sci. Alliance 6:e202301904 (2023).
- Pubmed
- Unoki, M., Velasco, G., Kori, S., Arita, K., Daigaku, Y., Au Yeung, W.K., Fujimoto, A., Ohashi, H., Kubota, T., Miyake, K. & Sasaki, H.
- Novel compound heterozygous mutations in UHRF1 are associated with atypical immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome with distinctive genome-wide DNA hypomethylation.
- Hum. Mol. Genet. 32:1439-1456 (2023).
- Pubmed
- Maruyama, O., Li, Y., Toh, H., Au Yeung, W.K. & Sasaki, H
- CMIC: Predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers.
- BMC Bioinform. 23:371 (2022).
- Pubmed
- Yano, S. Ishiuchi, T., Abe, S., Namekawa, S.H., Huang, G., Ogawa, Y. & Sasaki, H.
- Histone H3K36me2 and H3K36me3 form a chromatin platform essential for DNMT3A-dependent DNA methylation in mouse oocytes.
- Nat. Commun. 13, 4440 (2022).
- PubMed
- Inatomi, T., Matsuda, S., Ishiuchi, T., Do, Y., Nakayama, N., Abe, S., Kasho, K., Wanrooij, S., Nakada, K., Ichiyanagi, K., Sasaki, H., Yasukawa, T. & Kang. D.
- TFB2M and POLRMT are essential for mammalian mitochondrial DNA replication.
- Biochim. Biophys. Acta - Mol. Cell Res. 1869, 119167 (2022)
- PubMed
- Hasuwa, H., Iwasaki, Y.W., Au Yeung, W.K., Ishino, K., Masuda, H., Sasaki, H. & Siomi, H.
- Production of functional oocytes requires maternally expressed PIWI genes and piRNAs in golden hamsters.
- Nat. Cell Biol. 23, 1002-1012 (2021)
- PubMed
- Au Yeung, W.K., Maruyama, O. & Sasaki, H.
- A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns.
- BMC Bioinform. 22, 341 (2021)
- PubMed
- Haratake, N., Hu, Q., Okamoto, T., Jogo, T., Toyokawa, G., Kinoshita, F., Takenaka, T., Tagawa, T., Iseda, N., Itoh, S., Yamada, Y., Oda, Y., Shimokawa, M., Kikutake, C., Suyama, M., Unoki, M., Sasaki, H. & Mori, M.
- Identification of SLC38A7 as a prognostic marker and potentially targetable driver gene of lung squamous cell carcinoma.
- Ann. Surg. 274, 500-507 (2021)
- PubMed
- Kibe, K., Shirane, K., Ohishi, H., Uemura, S., Toh, H. & Sasaki, H.
- The DNMT3A PWWP domain is essential for the normal DNA methylation landscape in mouse somatic cells and oocytes.
- PLoS Genet. 17, e1009570 (2021)
- PubMed
- Morikawa, T., Ohishi, H., Kosaka, K., Shimojo T., Nagano, A., Taniguchi, I., Fujioka, R., Moriyama, K., Unoki, M., Takahashi, M., Nakao, M., Izumi, Y., Bamba, T., Sasaki, H., Miura, S. & Shibata, H.
- Ddhd1 knockout mouse as a model of locomotive and physiological abnormality in familial spastic paraplegia.
- Biosci. Rep. 41, BSR20204171 (2021)
- PubMed
- Ishiuchi, T., Abe, S., Inoue, K., Au Yeung, W.K., Miki, Y., Ogura, A. & Sasaki, H.
- Reprogramming of the histone H3.3 landscape in the early mouse embryo.
- Nat. Struct. Mol. Biol. 28, 38-49 (2021)
- PubMed
- Abe, S., Nagatomo, H., Sasaki, H. & Ishiuchi, T.
- A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation.
- Epigenetics 16, 1123-1134 (2021)
- PubMed
- Unoki, M., Sharif, J., Saito, Y., Velasco, G., Francastel, C., Koseki, H. & Sasaki, H.
- CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats.
- Sci. Rep. 10, 17865 (2020)
- PubMed
- Richard Albert, J., Au Yeung, W.K., Toriyama, K., Kobayashi, H., Hirasawa, R., Brind'Amour, J., Bogutz, A., Sasaki, H. & Lorincz, M.
- Maternal DNMT3A-dependent de novo methylation of the paternal genome inhibits gene expression in the early embryo.
- Nat. Commun. 11, 5417 (2020)
- PubMed
- Ohishi, H.*, Au Yeung, W.K.*, Unoki, M., Ichiyanagi, K., Fukuda, K., Maenohara, S., Shirane, K., Chiba, H., Sado, T. & Sasaki, H. (*These authors equally contributed to the work.)
- Characterization of genetic-origin-dependent monoallelic expression in mouse embryonic stem cells.
- Genes Cells 25, 54-64 (2020)
- PubMed
- Du, Z., Zheng, H., Kawamura, Y.K., Zhang, K., Gassler, J., Powell, S., Xu, Q., Lin, Z., Xu, K., Zhou, Q., Ozonov, E.A., Veron, N., Huang, B., Li, L., Yu, G., Liu, L., Au Yeung, W.K., Wang, P., Chang, L., Wang, Q., He, A., Sun, Y., Na, J., Sun, Q., Sasaki, H., Tachibana, K., Peters, A.H.F.M. & Xie, W.
- Polycomb group proteins regulate chromatin architecture in mouse oocytes and early embryos.
- Mol. Cell 77, 825-839 (2020)
- PubMed
- Hiramoto, T., Tahara, M., Liao, J., Soda, Y., Miura, Y., Kurita, R., Hamana, H., Inoue K., Kohara, H., Hijikata, Y., Okano, S., Yamaguchi, Y., Oda, Y., Ichiyanagi, K., Toh, H., Sasaki, H., Kishi, H., Ryo, A., Muraguchi, A., Takeda, M. & Tani, K.
- Non-transmissible MV vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells.
- Mol. Ther. 28, 129-141 (2020)
- PubMed
- Aktar, S., Sasaki, H. & Unoki, M.
- Identification of ZBTB24 protein domains and motifs for heterochromatin localization and transcriptional activation.
- Genes Cells 24, 746-755 (2019)
- PubMed
- Yamanaka, S., Nishihara, H., Toh, H., Nagai, L.A.E., Hashimoto, K., Park, S.J., Shibuya, A., Suzuki, A.M., Tanaka, Y., Nakai, K., Carninci, P., Sasaki, H. & Siomi, H.
- Broad heterochromatic domains open in gonocyte development prior to de novo DNA methylation.
- Dev. Cell 51, 21-34 (2019)
- PubMed
- Kanatsu-Shinohara, M., Yamamoto, T., Toh, H., Kazuki, Y., Imoto, J., Ikeo, K., Oshima, M., Shirahige, K., Iwama, A., Nabeshima, Y., Sasaki, H. & Shinohara, T.
- Aging of spermatogonial stem cells by Jnk-mediated glycolysis activation.
- Proc. Natl. Acad. Sci. USA 116, 16404-16409 (2019)
- PubMed
- Inoguchi, Y., Ichiyanagi, K., Ohishi, H., Maeda, Y., Sonoda, N., Ogawa, Y., Inoguchi, T. & Sasaki, H.
- Poorly controlled diabetes during pregnancy and lactation activates the Foxo1 pathway and causes glucose intolerance in adult offspring.
- Sci. Rep. 9, 10181 (2019)
- PubMed
- Ishiuchi, T., Ohishi, H., Sato, T., Kamimura, S., Yorino, M., Abe, S., Suzuki, A., Wakayama, T., Suyama, M. & Sasaki, H.
- Zfp281 shapes the transcriptome of trophoblast stem cells and is essential for placental development.
- Cell Rep. 27, 1742-1754 (2019)
- PubMed
- Au Yeung, W.K., Brind'Amour, J., Hatano, Y., Yamagata, K., Feil, R., Lorincz, M.C., Tachibana, M., Shinkai, Y. & Sasaki, H.
- Histone H3K9 methyltransferase G9a in oocytes is essential for preimplantation development but dispensable for CG methylation protection.
- Cell Rep. 27, 282-293 (2019)
- PubMed
- Kubo, N., Harada, T., Shiraishi, Y., Nosaki, K., Nakagaki, N., Takeshita, M., Ouchi, H., Iwama, E., Tanaka, K., Okamoto, I., Sasaki, H. & Nakanishi, Y.
- Identification of genomic alterations acquired during treatment with EGFR-TKIs in non-small cell lung cancer.
- Anticancer Res. 39, 671-677 (2019)
- PubMed
- Unoki, M., Funabiki, H., Velasco, G., Francastel, C. & Sasaki, H.
- CDCA7 and HELLS mutations undermine non-homologous end joining in centromeric instability syndrome.
- J. Clin. Invest. 129, 78-92 (2019)
- PubMed
- Kamae, C., Imai, K., Kato, T., Okano, T., Honma, K., Nakagawa, N., Yeh, T. W., Noguchi, E., Ohara, A., Shigemura, T., Takahashi, H., Takakura, S., Hayashi, M., Honma, A., Watanabe, S., Shigemori, T., Ohara, O., Sasaki, H., Kubota, T., Morio, T., Kanegae, H. & Nonoyama, S.
- Clinical and immunological characterization of ICF syndrome in Japan.
- J. Clin. Immunol. 38, 927-937 (2018)
- PubMed
- Yamashiro, C., Sasaki, K., Yabuta, Y., Kojima, Y., Nakamura, T., Okamoto, I., Yokobayashi, S., Murase, Y., Ishikura, I., Shirane, K., Sasaki, H., Yamamoto, T. & Saitou, M.
- Generation of human oogonia from induced pluripotent stem cells in vitro.
- Science 362, 356-360 (2018)
- PubMed
- Sakakibara, Y., Nagao, K., Blewitt, M., Sasaki, H., Obuse, C. & Sado, T.
- Role of SmcHD1 in establishment of epigenetic states required for the maintenance of the X-inactivated state in mice.
- Development 145, dev166462 (2018)
- PubMed
- Maezawa, S., Hasegawa, K., Yukawa, M., Kubo, N., Sakashita, A., Alabattam, K.G., Sin, H.S., Kartashov, A.V., Sasaki, H., Barski, A. & Namekawa, S.H.
- Polycomb protein SCML2 facilitates H3K27me3 to establish bivalent domains in the male germline.
- Proc. Natl. Acad. Sci. USA 115, 4957-4962 (2018)
- PubMed
- Matsuda, S., Yasukawa, T., Sakaguchi, Y., Ichiyanagi, K., Unoki, M., Gotoh, K., Fukuda, K., Sasaki, H., Suzuki, T. & Kang, D.
- Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA.
- Sci. Rep. 8, 5801 (2018)
- PubMed
- Okae, H., Toh, H., Sato, T., Hiura, H., Takahashi, S., Shirane, K., Kabayama, Y., Suyama, M., Sasaki, H. & Arima, T.
- Derivation of human trophoblast stem cells.
- Cell Stem Cell 22, 50-63 (2018)
- PubMed
- Suzuki, A., Kawano, S., Mituyama, T., Suyama, M., Kanai, Y., Shirahige, K., Sasaki, H., Tokunaga, K., Tsuchihara, K., Sugano, S., Nakai, K. & Suzuki, Y.
- DBTSS/DBKERO for integrated analysis of transcriptional regulation.
- Nucl. Acids Res. 46, D229-D238 (2018)
- PubMed
- Shimosuga, K., Fukuda, K., Sasaki, H. & Ichiyanagi, K.
- Locus-specific hypomethylation of the mouse IAP retrotransposon is associated with transcription factor-binding sites.
- Mobile DNA 8, 20 (2017)
- PubMed
- Maenohara, S., Unoki, M., Toh, H., Ohishi, H., Sharif, J., Koseki, H. & Sasaki, H.
- Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos.
- PLoS Genet. 13, e1007042. (2017)
- PubMed
- Chigi, Y., Sasaki, H. & Sado, T.
- The 5' region of Xist RNA has the potential to associate with chromatin through the A-repeat.
- RNA 23, 1894-1901 (2017)
- PubMed
- Inoue, K., Ichiyanagi, K., Fukuda, K., Glinka, M. & Sasaki, H.
- Switching of dominant retrotransposon silencing strategies from posttranscriptional to transcriptional mechanisms during male germ-cell development in mice.
- PLoS Genet. 13, e1006926 (2017)
- PubMed
- Sakata, Y., Nagao, K., Hoki, Y., Sasaki, H., Obuse, C. & Sado, T.
- Defects in dosage compensation impact global gene regulation in the mouse trophoblast.
- Development 144, 2784-2797 (2017)
- PubMed
- Fukuda, K., Inoguchi, Y., Ichiyanagi, K., Ichiyanagi, T., Go, Y., Nagano, M., Yanagawa, Y., Takaesu, N., Ohkawa, Y., Imai, H. & Sasaki, H.
- Evolution of the sperm methylome of primates is associated with retrotransposon insertions and genome instability.
- Hum. Mol. Genet. 26, 3508-3519 (2017)
- PubMed
- Ohta, H., Kurimoto, K., Okamoto, I., Nakamura, T., Yabuta, Y., Miyauchi, H., Yamamoto, T., Okuno, Y., Hagiwara, M., Shirane, K., Sasaki, H. & Saitou, M.
- In vitro expansion of mouse primordial germ cell-like cells recapitulates an epigenetic blank slate.
- EMBO J. 36, 1888-1907 (2017)
- PubMed
- Hidaka, N., Iwama, E., Kubo, N., Harada, T., Miyawaki, K., Tanaka, K., Okamoto, I., Baba, E., Akashi, K., Sasaki, H. & Nakanishi, Y.
- Most T790M mutations are present on the same EGFR allele as activating mutations in patients with non-small cell lung cancer.
- Lung Cancer 108, 75-82 (2017)
- PubMed
- Kabayama, Y., Toh, H., Katanaya, A., Sakurai, T., Chuma, S., Kuramochi-Miyagawa, S., Saga, Y., Nakano, T. & Sasaki, H.
- Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes.
- Nucl. Acids Res. 45, 5387-5398 (2017)
- PubMed
- Kobayashi, M., Kato, H., Hada, H., Itoh-Nakadai, A., Fujiwara, T., Muto, A., Inoguchi, Y., Ichiyanagi, K., Houjou, W., Tomosugi, N., Sasaki, H., Harigae, H. & Igarashi, K.
- Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency.
- Haematologica 102, 454-465 (2017)
- PubMed
- Toh, H., Shirane, K., Miura, F., Kubo, N., Ichiyanagi, K., Hayashi, K., Saitou, M., Suyama, M., Ito, T. & Sasaki, H.
- Software updates in the Illumina HiSeq platform affect whole-genome bisulfite sequencing.
- BMC Genomics 18, 31 (2017)
- PubMed
- Ishikura, Y., Yabuta, Y., Ohta, H., Hayashi, K., Nakamura, T., Okamoto, I., Yamamoto, T., Kurimoto, K., Shirane, K., Sasaki, H. & Saitou, M.
- In vitro derivation and propagation of spermatogonial stem cell activity from mouse pluripotent stem cells.
- Cell Rep. 17, 2789-2804 (2016)
- PubMed
- Hamada, H., Okae, H., Toh, H., Chiba, H., Hiura, H., Shirane, K., Sato, T., Suyama, M., Yaegashi, N., Sasaki, H. & Arima, T.
- Allele-specific methylome and transcriptome analysis reveals widespread imprinting in the human placenta.
- Am. J. Hum. Genet. 99, 1045-1058 (2016)
- PubMed
- Shirane, K., Kurimoto, K., Yabuta, Y., Yamaji, M., Satoh, J., Ito, S., Watanabe, A., Hayashi, K., Saitou, M. & Sasaki, H.
- Global landscape and regulatory principles of DNA methylation reprogramming for germ cell specification by mouse pluripotent stem cells.
- Dev. Cell 39, 87-103 (2016)
- PubMed
- Amouroux, R., Nashun, B., Shirane, K., Nakagawa, S., Hill, P.W., D'Souza, Z., Nakayama, M., Matsuda, M., Turp, A., Ndjetehe, E., Encheva, V., Kudo, N.R., Koseki, H., Sasaki, H. & Hajkova, P.
- De novo DNA methylation drives 5hmC accumulation in mouse zygotes.
- Nat. Cell Biol. 18, 225-233 (2016)
- PubMed
- Amakawa, Y., Sakata, Y., Hoki, Y., Arata, S., Shioda, S., Fukagawa, T., Sasaki, H. & Sado, T.
- A new Xist allele driven by a constitutively active promoter is dominated by Xist locus environment and exhibits the parent-of-origin effects.
- Development 142, 4299-4308 (2015)
- PubMed
- Kubo, N., Toh, H., Shirane, K., Shirakawa, T., Kobayashi, H., Sato, T., Sone, H., Sato, Y., Tomizawa, S., Tsurusaki, Y., Shibata, H., Saitsu, H., Suzuki, Y., Matumoto, N., Suyama, M., Kono, T., Ohbo, K. & Sasaki, H.
- DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis.
- BMC Genomics 16, 624 (2015)
- PubMed
- Thijssen, P.E., Ito, Y., Grillo, G., Wang, J., Velasco, G., Nitta, H., Unoki, M., Yoshihara, M., Suyama, M., Sun, Y., Lemmers, R.J.L.F., de Greef, J.C., Gennery, A., Picco, P., Kloeckener-Gruissem, B., Gungor, T., Reisli, I., Picard, C., Kebaili, K., Roquelaure, B., Iwai, T., Kondo, I., Kubota, T., van Ostaijen-Ten Dam, M.M., van Tol, M.J.D., Weemaes, C., Francastel, C., van der Maarel, S.M. & Sasaki. H.
- Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome.
- Nat. Commun. 6, 7870 (2015)
- PubMed
- Ichiyanagi, T., Ichiyanagi, K., Ogawa, A., Kuramochi-Miyagawa, S., Nakano, T., Chuma, S., Sasaki, H. & Udono, H.
- HSP90α plays an important role in piRNA biogenesis and retrotransposon repression in mouse.
- Nucl. Acids Res. 42, 11903-11911 (2014)
- PubMed
- Liu, S., Brind’Amour, J., Karimi, M.M., Shirane, K., Bogutz, A., Lefebvre, L., Sasaki, H., Shinkai, Y. & Lorincz, M.C.
- Setdb1 is required for germ line development and silencing of H3K9me3 marked endogenous retroviruses in primordial germ cells.
- Genes Dev. 28, 2041-2055 (2014)
- PubMed
- Velasco, G., Walton, L. E., Sterlin, D., Hedouin, S., Nitta, H., Ito, Y., Fouyssac F., Megarbane, A., Sasaki, H., Picard, C. & Francastel, C.
- Germline genes hypomethylation and expression define a molecular signature in peripheral blood of ICF patients: implications for diagnosis and etiology.
- Orphanet J. Rare Dis. 9, 56 (2014)
- PubMed
- Shiura, H., Okamoto, A., Sasaki, H. & Abe, K.
- Whole-mount MeFISH: a novel technique for simultaneous visualization of specific DNA methylation and protein/RNA expression.
- PLoS One 9, e95750 (2014)
- PubMed
- Liao, H.-F., Chen, W.S.C., Chen, Y.-H., Kao, T.-H., Tseng, Y.-T., Lee, C.-Y., Chiu, Y.-C., Lee, P.-L., Lin, Q.-J., Ching, Y.-H., Hata, K., Cheng, W.T.K., Tsai, M.-H., Sasaki, H., Ho, H.-N., Wu, S.-C. , Huang, Y.-H., Yen, P. & Lin, S.-P.
- DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells.
- Development 141, 2402-2413 (2014)
- PubMed
- Yokomizo, H., Inoguchi, T., Sonoda, N., Sakaki, Y., Maeda, Y., Inoue, T., Hirata, E., Takei, R., Ikeda, N., Fujii, M., Fukuda, K., Sasaki, H. & Takayanagi, R.
- Maternal high fat diet induces insulin resistance and deterioration of pancreatic β cell function in adult offspring with gender differences in mice.
- Am. J. Physiol. Endocrinol. Metab. 306, E1163-1175 (2014)
- PubMed
- Okae, H., Matoba, S. Nagashima, T., Mizutani, E., Inoue, K., Ogonuki, N., Chiba, H., Funayama, R., Tanaka, S., Yaegashi, N., Nakayama, K., Sasaki, H., Ogura, A. & Arima, T.
- RNA sequencing-based identification of aberrant imprinting in cloned mice.
- Hum. Mol. Genet. 23, 992-1001 (2014)
- PubMed
- Li, Y., Miyanari, Y., Shirane, K., Nitta, H., Kubota, T., Ohashi, H., Okamoto, A. & Sasaki, H.
- Sequence-specific microscopic visualization of DNA methylation status at satellite repeats in individual cell nuclei and chromosomes.
- Nucl. Acids Res. 41, e186 (2013)
- PubMed
- Nitta, H., Unoki, M., Ichiyanagi, K., Kosho, T., Shigemura, T., Takahashi, H., Velasco, G., Francastel, C., Picard, C., Kubota, T. & Sasaki, H.
- Three novel ZBTB24 mutations identified in Japanese and Cape Verdean type 2 ICF syndrome patients.
- J. Hum. Genet. 58, 455-460 (2013)
- PubMed
- Fukuda, K., Ichiyanagi, K., Yamada, Y., Go, Y., Udono, T., Wada, S., Maeda, T., Soejima, H., Saitou, N., Ito, T. & Sasaki, H.
- Regional DNA methylation differences between humans and chimpanzees are associated with genetic changes, transcriptional divergence and disease genes.
- J. Hum. Genet. 58, 446-454 (2013)
- PubMed
- Shirane, K., Toh, H., Kobayashi, H., Miura, F., Chiba, H., Ito, T., Kono, T. & Sasaki, H.
- Mouse oocyte methylomes at base resolution reveal genome-wide accumulation of non-CpG methylation and role of DNA methyltransferases.
- PLoS Genet. 9, e1003439 (2013)
- PubMed
- Unoki, M., Masuda, A., Dohmae, N., Arita, K., Yoshimatsu, M., Iwai, Y., Fukui, Y., Ueda, K., Hamamoto, R., Shirakawa, M., Sasaki, H. & Nakamura, Y.
- Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6).
- J. Biol. Chem. 288, 6053-6062 (2013)
- PubMed
- Yamamoto, Y., Watanabe, T., Hoki, Y., Shirane, K., Li, Y., Ichiyanagi, K., Kuramochi-Miyagawa, S., Toyoda, A., Fujiyama, A., Oginuma, M., Suzuki, H., Sado, T., Nakano, T. & Sasaki, H.
- Targeted gene silencing in mouse germ cells by insertion of a homologous DNA into a piRNA generating locus.
- Genome Res. 23, 292-299 (2013)
- PubMed
- Ichiyanagi, T., Ichiyanagi, K., Miyake, M. & Sasaki, H.
- Accumulation and loss of asymmetric non-CpG methylation during male germ-cell development.
- Nucl. Acids Res. 41, 738-745 (2013)
- PubMed
- Liu, Y., Toh, H., Sasaki, H., Zhang, X. & Cheng, X.
- An atomic model of ZFP57 recognition of CpG methylation within a specific DNA sequence.
- Genes Dev. 26, 2374-2379 (2012)
- PubMed
- Takahashi, T., Matsuzaki, H., Tomizawa, S., Okamura, E., Ichiyanagi, T., Fukamizu, A., Sasaki, H. & Tanimoto, K.
- Sequences in the H19 ICR that are transcribed as small RNA in oocytes are dispensable for methylation imprinting in YAC transgenic mice.
- Gene 508, 26-34 (2012)
- PubMed
- Okae, H., Hiura, H., Miyauchi, N., Abe, C., Nishida, Y., Funayama, R., Tanaka, S., Chiba, H., Yaegashi, N., Nakayama, K., Sasaki, H. & Arima, T.
- Re-investigation and RNA sequencing-based identification of genes with placenta-specific imprinted expression.
- Hum. Mol. Genet. 21, 548-558 (2012)
- PubMed
- Ohnishi, Y., Totoki, Y., Toyoda, A., Watanabe, T., Yamamoto, Y., Tokunaga, K., Sakaki, Y., Sasaki, H. & Hohjoh, H.
- Active role of small non-coding RNAs derived from SINE/B1 retrotransposon during early mouse development.
- Mol. Biol. Rep. 39, 903-909 (2012)
- PubMed
- Ichiyanagi, K., Li, Y., Watanabe, T., Ichiyanagi, T., Fukuda, K., Kitayama, J., Yamamoto, Y., Kuramochi-Miyagawa, S., Nakano, T., Yabuta, Y., Seki, Y., Saitou, M. & Sasaki, H.
- Locus- and domain-dependent control of DNA methylation at mouse B1 retrotransposons during male germ cell development.
- Genome Res. 21, 2058-2066 (2011)
- PubMed
- Watanabe, T., Tomizawa, S., Mitsuya, K., Totoki, Y., Yamamoto, Y., Kuramochi-Miyagawa, S., Iida, N., Hoki, Y., Murphy, P.J., Toyoda, A., Gotoh, K., Hiura, H., Arima, T., Fujiyama, A., Sado, T., Shibata, T., Nakano, T., Lin, H., Ichiyanagi, K., Soloway, P.D. & Sasaki, H.
- Role for piRNAs and non-coding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus.
- Science 332, 848-852 (2011)
- PubMed
- Hoki, Y., Ikeda, R., Mise, N., Sakata, Y., Ohhata, T., Sasaki, H., Abe, K. & Sado, T.
- Incomplete X-inactivation initiated by a hypomorphic Xist allele in the mouse
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- Biophilia 5, 6-10 (2009)
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- 千葉初音, 佐々木裕之
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- 実験医学 26, 2109-2111 (2008)
- 古海弘康, 佐々木裕之
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- 古海弘康, 佐々木裕之
- エピジェネティクス―疾患を見つめる新たな視点
- BIO Clinica 23, 155-159 (2008)
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- 佐々木裕之, 熊木健治, 小林久人, 加藤譲, 平澤竜太郎
- バイサルファイト法によるDNAメチル化解析の落とし穴 (クローズアップ実験法)
- 実験医学 25, 2191-2196 (2007)
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- エピジェネティクスがもたらす可能性
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- ゲノムDNAメチル化解析法
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- ゲノムインプリンティング
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- 実験医学別冊 羊土社(2020)
- 鵜木元香, 佐々木裕之
- 第5章: 生殖細胞形成と個体発生におけるエピジェネティクス
- エピジェネティクスの産業応用 (畑田出穂, 久保田健夫監修), 78-89, シーエムシー出版 (2014)
- 鵜木元香, 佐々木裕之
- 第2部-4: 生殖・発生
- エピジェネティクスキーワード事典 (牛島俊和, 真貝洋一編), 123-129, 羊土社 (2013)
- 佐々木裕之
- 2章:エピジェネティクス-DNAメチル化酵素の重要性
- 英語論文セミナー: 21世紀の分子生物学 (渡辺公綱, 桂勲編), 22-36, 講談社 (2013)
- 佐々木裕之
- 第22-17〜19章: エピジェネティクス, DNAメチル化, ゲノムインプリンティング
- 進化学事典 (日本進化学会編), 753-759, 共立出版 (2012)
- 佐々木裕之
- 第III-9章: エピジェネティクスの分子機構
- 卵子学 (森崇英総編集), 103-109, 京都大学学術出版会 (2011)
- 佐々木裕之
- 4章: ゲノムの高度活用戦略―エピジェネティクス
- 現代生物科学入門1 (浅島誠,黒岩常祥,小原雄治 編), 153-200, 岩波書店 (2009)
- 平澤竜太郎, 佐々木裕之
- 生殖細胞分化とエピジェネティクス
- 転写制御の分子生物学-ゲノムでコードに向けて (加藤茂明編), 63-72, 南山堂 (2008)
- 久須美真紀, 佐々木裕之
- 生殖・発生とエピジェネティクス
- 図説ARTマニュアル(改訂第2版) (森崇英, 久保春海, 岡村均 編), 492-496,永井書店 (2006)
- 平澤竜太郎, 佐々木裕之
- 第6章 DNAメチル化. 再生医療教科書シリーズ
- 第3巻 「再生医療のための分子生物学(仲野徹・赤池敏宏 監修)」 80-96,コロナ社(2006)
- 佐々木裕之
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- 岩波科学ライブラリー 岩波書店(2005)
- 佐々木裕之編
- エピジェネティクス
- Springer Reviews シリーズ シュプリンガー・フェアラーク東京(2004)
- 佐渡敬, 佐々木裕之
- 性染色体の構造と機能
- Springer Reviews シリーズ クロマチンと遺伝子機能制御 (堀越正美編), 15-24, シュプリンガー・フェアラーク東京 (2003)
- 横峯孝昭, 佐々木裕之
- ゲノムインプリンティングの進化
- Springer Reviews シリーズ ゲノムからみた生物の多様性と進化 (五條堀孝編), 164-170, シュプリンガー・フェアラーク東京 (2003)
- 佐々木裕之
- 単為発生とゲノムインプリンティング (第7章)
- バイオサイエンスの新世紀 第14巻「生命工学: 新しい生命へのアプローチ (浅島誠・山村研一編)」, 200-208, 共立出版 (2002)
- 佐々木裕之
- インプリンティング (第9章)
- 岩波講座-現代医学の基礎 第5巻「生殖と発生 (森崇英・山村研一編)」, 183-194, 岩波書店 (1999)
- 佐々木裕之
- 新しい遺伝概念「ゲノム刷り込み」と疾患
- 内科学進歩のトピックス (仁保喜之・石橋大海編), 6-8, 九州大学出版会 (1998)
- 佐々木裕之
- 23章 分子細胞遺伝学,C. ゲノム刷り込み現象
- 人類遺伝学 (柳瀬敏幸編), 226-230, 金原出版 (1995)
- 佐々木裕之
- ゲノム刷り込み現象
- 臨床DNA診断法 (古庄敏行・井村裕夫・中込弥男・岡田伸太郎・湯浅保仁・倉田毅編), 22-24, 金原出版 (1995)
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