The 26th Hot Spring Harbor International Symposium

−Trans-Omics: New Approaches in Biology and Medicine−

Medical Institute of Bioregulation, Kyushu University

 

November 2-3, 2016

Collaborative Research Station Hall I, Hospital Campus, Kyushu University, Fukuoka, JAPAN

 

 

Wednesday, November 2, 2016

10:00-10:05

Opening Remarks: Yusaku Nakabeppu (Director of Medical Institute of Bioregulation)

 

 

Session 1:

Signaling Networks                      Chair: Takeshi Bamba

10:05-10:30

S-01: Mariko Okada (Osaka University, Japan)

 

Multiple-scale cooperativity in signal-transcription network for cellular commitment 

 

 

10:30-10:55

S-02: Hiroyuki Kubota (Kyushu University, Japan)

 

Trans-omic analysis of insulin action-toward in vivo trans-omic analysis-

 

 

10:55-11:30

S-03: Uwe Sauer (ETH Zurich, Switzerland)

 

Coordination of metabolism through metabolite-protein interactions

 

 

11:30-11:40

Group Photos

11:40-13:00

Lunch (Transomics meeting by invitation only)

 

 

Session 2:

Transcription, Translation and Robustness  Chair: Mikita Suyama

13:00-13:25

S-04: Hisao Moriya (Okayama University, Japan)

 

Consequences of protein overexpression

 

13:25-13:50

S-05: Yasuyuki Ohkawa (Kyushu University, Japan)

 

The baseline of transcription level is determined by selective incorporation of histone H3 variants

 

 

13:50-14:25

S-06: Timothy J. Stasevich (Colorado State University, USA)

 

Real-time imaging of single mRNA translation dynamics in living cells

 

 

14:25-14:45

Coffee break

 

 

Session 3:

Short Talks by Young Scientists           Chair: Tohru Ishitani

14:45-16:45

Short talks of 12 minutes each (see p.4 for details)

 

 

16:45-17:05

Coffee break

 

 

Session 4:

Development and Differentiation          Chair: Atsushi Suzuki

17:05-17:30

S-07: Hiroyuki Sasaki (Kyushu University, Japan)

 

Multiple functions of the epigenetic regulator UHRF1 in mouse oocytes revealed by trans-omics approaches

 

 

17:30-17:55

S-08: Akira Nakamura (Kumamoto University, Japan)

 

Search for new factors that direct germ cell formation in the Drosophila embryo

 

 

17:55-18:20

S-9: Naoki Irie (University of Tokyo, Japan)

 

Why are vertebratesf organogenesis stages evolutionarily conservative?

 

 

19:00-

Dinner party (by invitation only)

 

 

 

 

 

 

 

 

 

Thursday, November 3, 2016

Session 5:

Disease_I                              Chair: Hiroki Shibata

10:30-10:55

S-10: Tatsuhiko Tsunoda (Tokyo Medical and Dental University, Japan)

 

Trans-omic analysis strategy for precision medicine

 

 

10:55-11:20

S-11: Yoshiyuki Minegishi (Tokushima University, Japan)

 

Identification of the molecular pathogenesis of hyper-IgE syndrome

 

 

11:20-11:55

S-12: Yong Hou (Beijing Genomics Institute, China)

 

Efforts to push single cell trans-omics for cancer research

 

 

11:55-13:30

Lunch

 

 

Session 6:

Disease_I I                             Chair: Yoshihiro Yamanishi

13:30-13:55

S-13: Keiichi Nakayama (Kyushu University, Japan)

 

Next-generation proteomics unveils a global landscape of
cancer metabolism

 

 

13:55-14:20

S-14: Jun Koseki (Osaka University, Japan)

 

Trans-omics analysis shows novel functional change in the ornithine metabolic pathway between cancer stem cells and non-cancer stem cells

 

 

14:20-14:55

S-15: Marie Evangelista (Genentech, USA)

 

Lessons from targeting metabolic dependencies in PDAC

 

 

14:55-15:00

Closing Remarks: Hiroyuki Sasaki (Kyushu University, Japan)

 

 

 


 

Session3: Short-Talk Session for Young Scientists   Chair: Tohru Ishitani

Wednesday, November, 2 2016

 

14:45-16:45  Short talks of 12 minutes each

 

Y-01: Shinjiro Hino (Kumamoto University, Japan)

Regulation of cellular metabolism by histone demethylase LSD1

 

Y-02: Kou Motani (Tokushima University, Japan)

Identification of STING-dependent secreted proteins using quantitative proteomic analysis

 

Y-03: Kenji Shimazu (Tokushima University, Japan)

Characterization of target genes for inhibitory co-receptor PD-1 by CAGE

 

Y-04: Yuki Kawasaki (Tokyo Medical and Dental University, Japan)

Development of the novel method gEnIGMAh for simultaneous identification of methylcytosine and hydroxymethylcytosine

 

Y-05: Yuki Akieda (Kyushu University, Japan)

Apoptosis-mediated elimination of "Wnt/ƒΐ-catenin signaling noise" supports precise embryonic patterning

 

Y-06: Yuta Katayama (Kyushu University, Japan)

CHD8 haploinsufficiency results in autistic-like phenotypes in mice

 

Y-07: Ryusuke Sawada (Kyushu University, Japan)

Transomics-based drug repositioning for a wide range of diseases

 

Y-08: Kai Inui (Kyushu University, Japan)

Analysis of nonsense-mediated mRNA decay (NMD) using genomic and transcriptomic data

 

Y-09: Yuuta Imoto (Kyushu University, Japan)

Post-genomic analysis of supramolecular nanomachinery for membrane-bounded organelle division

 

Y-10: Yuki Sohma (Kyushu University, Japan)

Metabolomics on designed metabolic dynamics by synthetic genetic circuits